Monster Slayer
Not unlocked yetEradicate 25 Heroic Monsters (marked by a Star).
Heroic Slayer
Not unlocked yetEradicate 100 Heroic Monsters (marked by a Star).
Legendary Slayer
Not unlocked yetEradicate 1000 Heroic Monsters (marked by a Star).
Nemesis
Not unlocked yetSlay a Nemesis monster on Elite or Ultimate Difficulty.
Unstoppable
Not unlocked yetSlay Six Nemesis monsters on Elite or Ultimate Difficulty.
Cleansing the World
Not unlocked yetRid Cairn of 25,000 Monsters.
A Wake of Carnage
Not unlocked yetRid Cairn of 50,000 Monsters.
An Ocean of Blood
Not unlocked yetRid Cairn of 100,000 Monsters.
Friends in the Apocalypse
Not unlocked yetReach Revered reputation with any Faction.
Paragon of Cairn
Not unlocked yetReach Revered reputation with 6 Factions.
Servant of Empyrion
Not unlocked yetReach Revered reputation with Kymon's Chosen.
Follower of Uroboruuk
Not unlocked yetReach Revered reputation with the Order of Death's Vigil.
The End to Depravity
Not unlocked yetSlay Salazar, Blade of Ch'thon in the Depraved Sanctuary.
Shattering the Blade of Ch'thon
Not unlocked yetSlay Salazar, Blade of Ch'thon in the Depraved Sanctuary on Ultimate Difficulty.
The Executioner Executed
Not unlocked yetSlay Alkamos, Lord Executioner in the Steps of Torment.
The End of Torment
Not unlocked yetSlay Alkamos, Lord Executioner in the Steps of Torment on Ultimate Difficulty.
Immortal Executioner
Not unlocked yetSlay Alkamos, Lord Executioner in the Steps of Torment on Hardcore Mode.
Delivering Justice
Not unlocked yetSlay Warden Krieg in the Hidden Laboratory.
An Old Threat
Not unlocked yetSlay Darius Cronley.
Blood for Blood
Not unlocked yetSlay Karroz, Sigil of Ch'thon.
The Bane of Cairn.
Not unlocked yetSlay the Loghorrean, Voice of Ch'thon.
Cleansing the Conflagration
Not unlocked yetSlay the Herald of Flame in the Conflagration.
Not Afraid of a Little Fire
Not unlocked yetSlay the Herald of Flame in the Conflagration on Ultimate Difficulty.
Gutting Gutworm
Not unlocked yetSlay Gutworm in Smuggler's Basin.