Perfect Clear: All Bosses
Not unlocked yetBeat each base game boss with a perfect clear, also not using missiles or consumables.
Perfect Clear: Crystal Mother
Not unlocked yetBeat the boss "Crystal Mother" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Battleswarm
Not unlocked yetBeat the boss "Battleswarm" with a perfect clear, also not using missiles or consumables.
Perfect Clear: WallMaster
Not unlocked yetBeat the boss "WallMaster" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Mirror
Not unlocked yetBeat the boss "Mirror" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Backfire
Not unlocked yetBeat the boss "Backfire" with a perfect clear, also not using missiles or consumables.
Perfect Clear: ShrapnelRose
Not unlocked yetBeat the boss "ShrapnelRose" with a perfect clear, also not using missiles or consumables.
Perfect Clear: LadyStaccato
Not unlocked yetBeat the boss "LadyStaccato" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Labyrinth
Not unlocked yetBeat the boss " Labyrinth" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Aggressor
Not unlocked yetBeat the boss "Aggressor" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Centrifuge
Not unlocked yetBeat the boss "Centrifuge" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Vestige
Not unlocked yetBeat the boss "Vestige" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Fusillade
Not unlocked yetBeat the boss "Fusillade" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Aberration
Not unlocked yetBeat the boss "Aberration" with a perfect clear, also not using missiles or consumables.
Perfect Clear: The Warden
Not unlocked yetBeat the boss "The Warden" with a perfect clear, also not using missiles or consumables.
Perfect Clear: Terminus
Not unlocked yetBeat the boss "Terminus" with a perfect clear, also not using missiles or consumables.
Perfect Clear: All Mini Bosses
Not unlocked yetBeat each miniboss with a perfect clear, also not using missiles or consumables.
Clear All Condemned Bosses
Not unlocked yetBeat each condemned boss.
Untouchable
Not unlocked yetComplete a floor with no damage.
Conspicuous Nonconsumption
Not unlocked yetComplete a run without buying any items.
Noncommittal
Not unlocked yetComplete a run without picking up any attachment items.
Unlock All Items
Not unlocked yetSatisfy the unlock conditions for all items.
Find All Items
Not unlocked yetActually find (pick up) every single item.
Safari
Not unlocked yetKill at least one of each non-boss enemy.