Have 25 Move Speed and 50% Damage as the Plague Doctor

Apply Plague to 50 enemies at the same time.

Conquer 10 Points of Interest in a single run

Collect 30 gems in a single run.

Have 3 weapons socketed with gems.

Have 5 summoned units active at the same time.

Have 50 Summon Power and 50 Magic Power

Have 50 Summon Power and 50 Projectile Power

Have 100% crit chance as the Plague Specter.

Kill 10 Elite enemies using Plague status as the Plague Patron.

As the Collector, have a Masterwork-tier gem for each gem size.

As the Jeweller, socket 2 tier Masterwork Gems into a weapon.

As the Necromancer, have 20 Undead units active at the same time.

As the Artificer, win using only Automaton and Projectile weapons

Have 25 summoned units active at the same time.

Complete 5 Summoning Circles in a single run.

Break 20 Gold Statues in one run.

Have a tier 4 Undead, Automaton, and Elemental unit active at the same time.

Apply Burn to 25 enemies at the same time.